Dietmar Zehn : rechercher sur Z-Library

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1

More promiscuity resulting in more tolerance

Zehn, Dietmar, Bevan, Michael J

Journal:

Nature Immunology

Année:

2007

Langue:

english

Fichier:

PDF, 368 KB

english, 2007

2

TCR signaling requirements for activating T cells and for generating memory

Dietmar Zehn, Carolyn King, Michael J. Bevan, Ed Palmer

Journal:

Cellular and Molecular Life Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 320 KB

english, 2012

3

T cell differentiation in chronic infection and cancer: functional adaptation or exhaustion?

Speiser, Daniel E., Utzschneider, Daniel T., Oberle, Susanne G., Münz, Christian, Romero, Pedro, Zehn, Dietmar

Journal:

Nature Reviews Immunology

Année:

2014

Langue:

english

Fichier:

PDF, 935 KB

english, 2014

4

Immune-surveillance through exhausted effector T-cells

Zehn, Dietmar, Utzschneider, Daniel T, Thimme, Robert

Journal:

Current Opinion in Virology

Année:

2016

Langue:

english

Fichier:

PDF, 416 KB

english, 2016

5

High antigen levels induce an exhausted phenotype in a chronic infection without impairing T cell expansion and survival

Utzschneider, Daniel T., Alfei, Francesca, Roelli, Patrick, Barras, David, Chennupati, Vijaykumar, Darbre, Stephanie, Delorenzi, Mauro, Pinschewer, Daniel D., Zehn, Dietmar

Journal:

Journal of Experimental Medicine

Année:

2016

Langue:

english

Fichier:

PDF, 2.42 MB

english, 2016

6

Transcription Factor IRF4 Promotes CD8 + T Cell Exhaustion and Limits the Development of Memory-like T Cells during Chronic Infection

Man, Kevin, Gabriel, Sarah S., Liao, Yang, Gloury, Renee, Preston, Simon, Henstridge, Darren C., Pellegrini, Marc, Zehn, Dietmar, Berberich-Siebelt, Friederike, Febbraio, Mark A., Shi, Wei, Kallies, A

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 4.96 MB

english, 2017

7

Origin and fine-tuning of effector CD8 T cell subpopulations in chronic infection

Kanev, Kristiyan, Zehn, Dietmar

Journal:

Current Opinion in Virology

Année:

2021

Fichier:

PDF, 436 KB

2021

8

Extended presentation of specific MHC-peptide complexes by mature dendritic cells compared to other types of antigen-presenting cells

Dietmar Zehn, Cyril J. Cohen, Yoram Reiter, Peter Walden

Journal:

European Journal of Immunology

Année:

2004

Langue:

english

Fichier:

PDF, 182 KB

english, 2004

9

Complete but curtailed T-cell response to very low-affinity antigen

Zehn, Dietmar, Lee, Sarah Y., Bevan, Michael J.

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2009

10

T Cells with Low Avidity for a Tissue-Restricted Antigen Routinely Evade Central and Peripheral Tolerance and Cause Autoimmunity

Dietmar Zehn, Michael J. Bevan

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 540 KB

english, 2006

11

T Cell Affinity Regulates Asymmetric Division, Effector Cell Differentiation, and Tissue Pathology

King, Carolyn G., Koehli, Sabrina, Hausmann, Barbara, Schmaler, Mathias, Zehn, Dietmar, Palmer, Ed

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 1.44 MB

english, 2012

12

T cells maintain an exhausted phenotype after antigen withdrawal and population reexpansion

Utzschneider, Daniel T, Legat, Amandine, Fuertes Marraco, Silvia A, Carrié, Lucie, Luescher, Immanuel, Speiser, Daniel E, Zehn, Dietmar

Journal:

Nature Immunology

Année:

2013

Langue:

english

Fichier:

PDF, 970 KB

english, 2013

13

IL-12-mediated STAT4 signaling and TCR signal strength cooperate in the induction of CD40L in human and mouse CD8 + T cells

Stark, Regina, Hartung, Anett, Zehn, Dietmar, Frentsch, Marco, Thiel, Andreas

Journal:

European Journal of Immunology

Année:

2013

Langue:

english

Fichier:

PDF, 465 KB

english, 2013

14

Bystander-Activated Memory CD8 T Cells Control Early Pathogen Load in an Innate-like, NKG2D-Dependent Manner

Chu, Talyn, Tyznik, Aaron J., Roepke, Sarah, Berkley, Amy M., Woodward-Davis, Amanda, Pattacini, Laura, Bevan, Michael J., Zehn, Dietmar, Prlic, Martin

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 724 KB

english, 2013

15

The effect of vaccines based on ovalbumin coupled to gas-filled microbubbles for reducing infection by ovalbumin-expressing Listeria monocytogenes

Bioley, Gilles, Zehn, Dietmar, Lassus, Anne, Terrettaz, Jacques, Tranquart, François, Corthésy, Blaise

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 1015 KB

english, 2013

16

PTPN2 restrains CD8+ T cell responses after antigen cross-presentation for the maintenance of peripheral tolerance in mice

Wiede, Florian, Ziegler, Alexandra, Zehn, Dietmar, Tiganis, Tony

Journal:

Journal of Autoimmunity

Année:

2014

Langue:

english

Fichier:

PDF, 2.81 MB

english, 2014

17

Affinity-dependent effects of Teriflunomide and impact on T cell metabolism

Eschborn, Melanie, Lindner, Maren, Posevitz, Vilmos, Zehn, Dietmar, Wiendl, Heinz, Klotz, Luisa

Journal:

Journal of Neuroimmunology

Année:

2014

Langue:

english

Fichier:

PDF, 59 KB

english, 2014

18

Optimal T-cell receptor affinity for inducing autoimmunity

Koehli, Sabrina, Naeher, Dieter, Galati-Fournier, Virginie, Zehn, Dietmar, Palmer, Ed

Journal:

Proceedings of the National Academy of Sciences

Année:

2014

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2014

19

Molecular Insights for Optimizing T Cell Receptor Specificity Against Cancer

Hebeisen, Michael, Oberle, Susanne G., Presotto, Danilo, Speiser, Daniel E., Zehn, Dietmar, Rufer, Nathalie

Journal:

Frontiers in Immunology

Année:

2013

Langue:

english

Fichier:

PDF, 688 KB

english, 2013

20

Inhibitory Receptor Expression Depends More Dominantly on Differentiation and Activation than “Exhaustion” of Human CD8 T Cells

Legat, Amandine, Speiser, Daniel E., Pircher, Hanspeter, Zehn, Dietmar, Fuertes Marraco, Silvia A.

Journal:

Frontiers in Immunology

Année:

2013

Langue:

english

Fichier:

PDF, 5.46 MB

english, 2013

21

Functional Avidity: A Measure to Predict the Efficacy of Effector T Cells?

Viganò, Selena, Utzschneider, Daniel T., Perreau, Matthieu, Pantaleo, Giuseppe, Zehn, Dietmar, Harari, Alexandre

Journal:

Clinical & Developmental Immunology

Année:

2012

Langue:

english

Fichier:

PDF, 877 KB

english, 2012

22

Mammalian Target of Rapamycin Complex 2 Controls CD8 T Cell Memory Differentiation in a Foxo1-Dependent Manner

Zhang, Lianjun, Tschumi, Benjamin O., Lopez-Mejia, Isabel C., Oberle, Susanne G., Meyer, Marten, Samson, Guerric, Rüegg, Markus A., Hall, Michael N., Fajas, Lluis, Zehn, Dietmar, Mach, Jean-Pierre, Do

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 3.86 MB

english, 2016

23

Role of proapoptotic BH3-only proteins in Listeria monocytogenes infection

Margaroli, Camilla, Oberle, Susanne, Lavanchy, Christine, Scherer, Stefanie, Rosa, Muriel, Strasser, Andreas, Pellegrini, Marc, Zehn, Dietmar, Acha-Orbea, Hans, Ehirchiou, Driss

Journal:

European Journal of Immunology

Année:

2016

Langue:

english

Fichier:

PDF, 1.51 MB

english, 2016

24

pMHC affinity controls duration of CD8 + T cell–DC interactions and imprints timing of effector differentiation versus expansion

Ozga, Aleksandra J., Moalli, Federica, Abe, Jun, Swoger, Jim, Sharpe, James, Zehn, Dietmar, Kreutzfeldt, Mario, Merkler, Doron, Ripoll, Jorge, Stein, Jens V.

Journal:

Journal of Experimental Medicine

Année:

2016

Langue:

english

Fichier:

PDF, 3.01 MB

english, 2016

25

NLRC5 shields T lymphocytes from NK-cell-mediated elimination under inflammatory conditions

Ludigs, Kristina, Jandus, Camilla, Utzschneider, Daniel T., Staehli, Francesco, Bessoles, Stéphanie, Dang, Anh Thu, Rota, Giorgia, Castro, Wilson, Zehn, Dietmar, Vivier, Eric, Held, Werner, Romero, Pe

Journal:

Nature Communications

Année:

2016

Langue:

english

Fichier:

PDF, 863 KB

english, 2016

26

A Minimum Epitope Overlap between Infections Strongly Narrows the Emerging T Cell Repertoire

Oberle, Susanne G., Hanna-El-Daher, Layane, Chennupati, Vijaykumar, Enouz, Sarah, Scherer, Stefanie, Prlic, Martin, Zehn, Dietmar

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 1.72 MB

english, 2016

27

Type I interferons induced by endogenous or exogenous viral infections promote metastasis and relapse of leishmaniasis

Rossi, Matteo, Castiglioni, Patrik, Hartley, Mary-Anne, Eren, Remzi Onur, Prével, Florence, Desponds, Chantal, Utzschneider, Daniel T., Zehn, Dietmar, Cusi, Maria G., Kuhlmann, F. Matthew, Beverley, S

Journal:

Proceedings of the National Academy of Sciences

Année:

2017

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2017

28

TCF1+ hepatitis C virus-specific CD8+ T cells are maintained after cessation of chronic antigen stimulation

Wieland, Dominik, Kemming, Janine, Schuch, Anita, Emmerich, Florian, Knolle, Percy, Neumann-Haefelin, Christoph, Held, Werner, Zehn, Dietmar, Hofmann, Maike, Thimme, Robert

Journal:

Nature Communications

Année:

2017

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2017

29

T Cell Exhaustion: An Epigenetically Imprinted Phenotypic and Functional Makeover

Alfei, Francesca, Zehn, Dietmar

Journal:

Trends in Molecular Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 512 KB

english, 2017

30

Resistance to TGFβ suppression and improved anti-tumor responses in CD8+ T cells lacking PTPN22

Brownlie, Rebecca J., Garcia, Celine, Ravasz, Mate, Zehn, Dietmar, Salmond, Robert J., Zamoyska, Rose

Journal:

Nature Communications

Année:

2017

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2017

31

Shp-2 Is Dispensable for Establishing T Cell Exhaustion and for PD-1 Signaling In Vivo

Rota, Giorgia, Niogret, Charlène, Dang, Anh Thu, Barros, Cristina Ramon, Fonta, Nicolas Pierre, Alfei, Francesca, Morgado, Leonor, Zehn, Dietmar, Birchmeier, Walter, Vivier, Eric, Guarda, Greta

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 2.26 MB

english, 2018

32

Inhibition of mTORC2/Akt signaling to enhance the therapeutic potential of CD8 T cells

Zhang, Lianjun, Tschumi, Benjamin, Oberle, Susanne, Ruegg, Markus, Hall, Michael, Zehn, Dietmar, Mach, Jean-Pierre, Donda, Alena, Romero, Pedro

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 246 KB

english, 2015

33

Strong homeostatic TCR signals induce formation of self‐tolerant virtual memory CD8 T cells

Drobek, Ales, Moudra, Alena, Mueller, Daniel, Huranova, Martina, Horkova, Veronika, Pribikova, Michaela, Ivanek, Robert, Oberle, Susanne, Zehn, Dietmar, McCoy, Kathy D, Draber, Peter, Stepanek, Ondrej

Journal:

The EMBO Journal

Année:

2018

Langue:

english

Fichier:

PDF, 3.05 MB

english, 2018

34

PD-1 Blockade Unleashes Effector Potential of Both High- and Low-Affinity Tumor-Infiltrating T Cells

Martínez-Usatorre, Amaia, Donda, Alena, Zehn, Dietmar, Romero, Pedro

Journal:

The Journal of Immunology

Année:

2018

Langue:

english

Fichier:

PDF, 2.77 MB

english, 2018

35

Exacerbated Leishmaniasis Caused by a Viral Endosymbiont can be Prevented by Immunization with Its Viral Capsid

Castiglioni, Patrik, Hartley, Mary-Anne, Rossi, Matteo, Prevel, Florence, Desponds, Chantal, Utzschneider, Daniel T., Eren, Remzi-Onur, Zangger, Haroun, Brunner, Livia, Collin, Nicolas, Zehn, Dietmar,

Journal:

PLoS Neglected Tropical Diseases

Année:

2017

Langue:

english

Fichier:

PDF, 1.96 MB

english, 2017

36

Leveraging TCR affinity in adoptive immunotherapy against shared tumor/self antigens

Miller, Aaron M, Bahmanof, Milad, Zehn, Dietmar, Cohen, Ezra E.W., Schoenberger, Stephen P

Journal:

Cancer Immunology Research

Année:

2018

Langue:

english

Fichier:

PDF, 13.21 MB

english, 2018

37

Precursor exhausted T cells: key to successful immunotherapy?

Kallies, Axel, Zehn, Dietmar, Utzschneider, Daniel T.

Journal:

Nature Reviews Immunology

Année:

2019

Langue:

english

Fichier:

PDF, 1.56 MB

english, 2019

38

Dynamics of the Coreceptor-LCK Interactions during T Cell Development Shape the Self-Reactivity of Peripheral CD4 and CD8Â T Cells

Horkova, Veronika, Drobek, Ales, Mueller, Daniel, Gubser, Celine, Niederlova, Veronika, Wyss, Lena, King, Carolyn G., Zehn, Dietmar, Stepanek, Ondrej

Journal:

Année:

2020

Fichier:

PDF, 2.61 MB

2020

39

Proliferation-competent Tcf1+ CD8 T cells in dysfunctional populations are CD4 T cell help independent

Kanev, Kristiyan, Wu, Ming, Drews, Antar, Roelli, Patrick, Wurmser, Christine, von HÃ¶sslin, Madlaina, Zehn, Dietmar

Journal:

Proceedings of the National Academy of Sciences

Année:

2019

Langue:

english

Fichier:

PDF, 1.08 MB

english, 2019

40

Cell-intrinsic adrenergic signaling controls the adaptive NK cell response to viral infection

Diaz-Salazar, Carlos, Bou-Puerto, Regina, Mujal, Adriana M., Lau, Colleen M., von Hoesslin, Madlaina, Zehn, Dietmar, Sun, Joseph C.

Journal:

Journal of Experimental Medicine

Année:

2020

Fichier:

PDF, 3.16 MB

2020

41

Two parallel worlds of memory T cells

Chu, Talyn, Berner, Jacqueline, Zehn, Dietmar

Journal:

Nature Immunology

Année:

2020

Fichier:

PDF, 945 KB

2020